Depo shot side effects long term - Jan 11, 2023 · Appropriate Use. The Depo-Provera birth control shot has advantages and disadvantages compared to other types of birth control. While it's convenient and effective, for example, the Depo shot also carries the risk of side effects like irregular bleeding and bone loss. This article looks at some of the pros and cons of using Depo-Provera.

 
The use of Depo-Provera CI is not recommended as a long-term (i.e., longer than 2 years) birth control method unless other options are considered inadequate. BMD should be evaluated when a woman needs to continue to use Depo-Provera CI long-term. In adolescents, interpretation of BMD results should take into account patient age and skeletal ... . Houses for rent in ocala fl under dollar1200

Purpose and method: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women ...A prospective analysis of women using Depo-Provera found no change in sexual function after four months, and women using progestin-only pills had no difference in sexual desire compared with those ...Mar 23, 2022 · Other long-term birth control options include the: ... The Depo-Provera shot needs to be administered every three months. The birth control implant works for three years. ... Side effects usually ... Medroxyprogesterone acetate. Medroxyprogesterone acetate ( MPA ), also known as depot medroxyprogesterone acetate ( DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [9] [3] It is used as a method of birth control and as a part of menopausal hormone therapy.Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ...Examples include birth control pills, as well as the vaginal ring (NuvaRing), skin patch (Xulane) and contraceptive injection (Depo-Provera). These are considered short-acting methods because you have to remember to use them on a daily, weekly or monthly basis. Long-acting hormonal methods.Dec 14, 2001 · Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ... Depo-Provera use may also delay the return of your fertility. About 50% of women will be able to get pregnant within 10 months after their last Depo-Provera injection, but it can take up to 18 months for fertility to return. Some women report irregular or continuous bleeding when using Depo-Provera along with other unwanted side effects.Find patient medical information for Depo-Medrol injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... during long-term treatment ...Aug 1, 2023 · lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients. Jun 22, 2023 · People who had severe illness with COVID-19 might experience organ damage affecting the heart, kidneys, skin and brain. Inflammation and problems with the immune system can also happen. It isn't clear how long these effects might last. The effects also could lead to the development of new conditions, such as diabetes or a heart or nervous ... Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%). Depo-Provera Vial Contraceptives. - Uses, Side Effects, This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with ... Mar 5, 2023 · Very common (10% or more): Increase weight (up to 37%) Common (1% to 10%): Increased appetite, decreased appetite. Uncommon (0.1% to 1%): Diabetes mellitus exacerbated, hypercalcemia, fluid retention. Frequency not reported: Elevations of serum calcium and potassium levels, exacerbation of diabetes mellitus. You might notice: Uneven menstrual periods or no periods at all Headaches Nervousness Depression Dizziness Acne Changes in appetite Weight gain Unwanted facial and body hair Hair loss Loss of bone mineral density Belly pain Bloating Breakthrough bleeding Fatigue Less interest in sex Weakness ... Aug 9, 2023 · Depo-Provera use may also delay the return of your fertility. About 50% of women will be able to get pregnant within 10 months after their last Depo-Provera injection, but it can take up to 18 months for fertility to return. Some women report irregular or continuous bleeding when using Depo-Provera along with other unwanted side effects. weakness near the injection site; Long-term side effects. Taking steroid shots for a prolonged period of time increases the risk of more serious side effects. Long-term side effects can include:The most commonly reported side effects were hot flashes or sweats, gastrointestinal disorders, hyperhidrosis, edema, emotional lability or depression, respiratory disorder, urinary disorder, nausea or vomiting, injection site reaction, joint disorders, testicular atrophy, asthenia, flu syndrome, headache, skin reaction, fatigue, and pain.Uses. Warnings: This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with longer use of this medication and smoking ... May 2, 2023 · Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Depression or other mood changes. Eyesight changes or loss, bulging eyes, or change in how contact lenses feel. A lump in the breast, breast pain or soreness, or nipple discharge. Flu -like signs. Mar 6, 2023 · Lupron is a drug doctors prescribe to treat prostate cancer. It works by reducing testosterone levels in the body, slowing cancer growth. Lupron is the brand name for leuprolide acetate. Lupron ... Testosterone cypionate (Depo-testosterone) is an injectable drug used to treat hypogonadism in males. Learn about side effects, warnings, dosage, and more.Depo-Provera Vial Contraceptives. - Uses, Side Effects, This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with ...Very common (10% or more): Increase weight (up to 37%) Common (1% to 10%): Increased appetite, decreased appetite. Uncommon (0.1% to 1%): Diabetes mellitus exacerbated, hypercalcemia, fluid retention. Frequency not reported: Elevations of serum calcium and potassium levels, exacerbation of diabetes mellitus.Feb 22, 2022 · They might include: Abdominal pain Bloating Decreased interest in sex Depression Dizziness Headaches Irregular periods and breakthrough bleeding Nervousness Weakness and fatigue Weight gain Appropriate Use. The Depo-Provera birth control shot has advantages and disadvantages compared to other types of birth control. While it's convenient and effective, for example, the Depo shot also carries the risk of side effects like irregular bleeding and bone loss. This article looks at some of the pros and cons of using Depo-Provera.When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ...Dec 1, 2009 · Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine and provides another option for maintenance treatment of schizophrenia. As with oral olanzapine, weight gain and metabolic effects (raised serum cholesterol, triglyceride and glucose levels) are common. Establish tolerability and response to oral ... altered interest in having sexual intercourse. abnormal bleeding from the uterus. a problem with menstrual periods. dizziness. weight gain. headache. nervousness. reactions at the site of the ...Jan 6, 2022 · Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction. SU. suzanne66 7 March 2010. Chemical castration (as it is referred to in males) by using Depo-provera lowers testosterone and reduces sex drive. Males can have sexual intercourse but do not want to. It also discourages sexual fantasies and eradicates sexual obsessions. Mood changes and depression are reported side-effects of depo-provera.I got the Depo shot on Feburary 8th, 2017. The first two weeks afterwards I felt fine, surprisingly no side effects so I was happy about getting it. However, when the third week started, all hell started to break lose. Mood swings, severe depression, OCD, severe anxiety, loss of sex drive, constant spotting, loss of attraction to my BF, and ...Potential side effects of cortisone shots increase with larger doses and repeated use. Side effects can include: Cartilage damage. Death of nearby bone. Joint infection. Nerve damage. Temporary facial flushing. Temporary flare of pain and inflammation in the joint. Temporary increase in blood sugar.Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ...Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction.Uses. Warnings: This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with longer use of this medication and smoking ... A further benefit of depot treatment is the achievement of stable plasma concentrations over long periods, allowing injections to be given every few weeks. However, this also represents a potential disadvantage in that there is a lack of flexibility of administration. Should adverse effects develop, the drug cannot be rapidly withdrawn.Jun 15, 2022 · Loss of bone density, if Lupron Depot is taken long term. Convulsions (violent shaking, seizures). Problems with your heart’s electrical activity, such as long QT syndrome . LousArk 24 Nov 2017. The Manufacturer recommends that you not use Depo Provera long term (more than 2 years), unless you have no option. In that case, you need to take the recommended breaks every couple of years. They state that it can take up to 18 months from the point you miss your shot, for your fertility to return.The most commonly reported side effects were hot flashes or sweats, gastrointestinal disorders, hyperhidrosis, edema, emotional lability or depression, respiratory disorder, urinary disorder, nausea or vomiting, injection site reaction, joint disorders, testicular atrophy, asthenia, flu syndrome, headache, skin reaction, fatigue, and pain.Medroxyprogesterone acetate. Medroxyprogesterone acetate ( MPA ), also known as depot medroxyprogesterone acetate ( DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [9] [3] It is used as a method of birth control and as a part of menopausal hormone therapy.lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients.Apr 25, 2023 · When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ... Good advice below - re: leaving your ovaries in! I had my one and only grand mal seizure on the day I got my period back - about 6 months after taking my last Depo Provera shot. I only took 2 injections of the drug but stopped it due to concerns about loss of bone density and the strange periods that I was having. Jul 1, 2021 · There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ... Dec 1, 2009 · Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine and provides another option for maintenance treatment of schizophrenia. As with oral olanzapine, weight gain and metabolic effects (raised serum cholesterol, triglyceride and glucose levels) are common. Establish tolerability and response to oral ... Nov 12, 2020 · This article highlights medroxyprogesterone as it is used as contraception to prevent pregnancy. This activity discusses the mechanism of action, adverse effects, monitoring, and contraindications for medroxyprogesterone. Also, it highlights the important role that providers play in administering medroxyprogesterone and regularly monitoring patients for side effects. lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients.To go off of this form of birth control, just don’t get your next shot. But be aware that your periods and fertility may take more than the initial three months to return. “In some people, it ...Examples include birth control pills, as well as the vaginal ring (NuvaRing), skin patch (Xulane) and contraceptive injection (Depo-Provera). These are considered short-acting methods because you have to remember to use them on a daily, weekly or monthly basis. Long-acting hormonal methods.There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ...A prospective analysis of women using Depo-Provera found no change in sexual function after four months, and women using progestin-only pills had no difference in sexual desire compared with those ...Purpose and method: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women ...You should talk to your healthcare provider about any possible side effects of Depo-Provera®. Most of these side effects are not common. Changes in your menstrual cycle is the most common side effect that women experience. You may experience irregular bleeding or spotting. After a year of use, about 50% of women will stop getting their periods.Medical side effects: The results of two major world studies have shown that women who take Depo-Provera for two years or more before age 25 have at least a 190% increased risk of developing ...Depo-Provera is an injection that prevents pregnancy for 3 months at a time. It contains a synthetic hormone called progestin. The birth control shot works similarly to the pill by preventing ...Dec 14, 2001 · Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ... Satisfaction. I'm a 40 yr. old that has been taking Depo-Provera for about 11 years. I like it all except, that I have to go to the doctor every 3 months and I do have the shakes and anxiety, heart palpitations, etc. BUT I also had anxiety before so not exactly sure if the shot is causing it. Also I do feel tired alot.Oct 1, 2022 · Lifestyle Changes. Depo-Provera ( depot medroxyprogesterone acetate , or DMPA) is an effective and relatively easy form of birth control. It does appear to cause weight gain for many women, though. Weight gain is often cited as the reason women stop using the shots. DMPA can change body composition and increase fat mass. Long-term case-controlled surveillance of users of Depo-Provera CI found no overall increased risk of ovarian or liver cancer. 5.4 Ectopic Pregnancy Be alert to the possibility of an ectopic pregnancy among women using Depo-Provera CI who become pregnant or complain of severe abdominal pain.Oct 1, 2022 · Lifestyle Changes. Depo-Provera ( depot medroxyprogesterone acetate , or DMPA) is an effective and relatively easy form of birth control. It does appear to cause weight gain for many women, though. Weight gain is often cited as the reason women stop using the shots. DMPA can change body composition and increase fat mass. A further benefit of depot treatment is the achievement of stable plasma concentrations over long periods, allowing injections to be given every few weeks. However, this also represents a potential disadvantage in that there is a lack of flexibility of administration. Should adverse effects develop, the drug cannot be rapidly withdrawn. Rated Depo-Provera for Endometriosis Report . I was always happy and outgoing. Always with friends or making new friends to hang with. After almost 2 years on this drug I am: • Severely depressed • crazy anxiety • antisocial ( I try but I don’t ever want to be with people or do anything the more I get this shot ) • I don’t feel attracted to anyone • I cry everyday at least 5 ...Depo Medrol 80 MG Injection is used for treating Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout. Psoriasis. Depo Medrol 80 MG Injection is used to cure Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis. Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women.weakness near the injection site; Long-term side effects. Taking steroid shots for a prolonged period of time increases the risk of more serious side effects. Long-term side effects can include:A further benefit of depot treatment is the achievement of stable plasma concentrations over long periods, allowing injections to be given every few weeks. However, this also represents a potential disadvantage in that there is a lack of flexibility of administration. Should adverse effects develop, the drug cannot be rapidly withdrawn.Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone.So I have been on depo for about two years now and have never had severe problems. I have noticed since starting Depo that I have more vaginal discharge, more acne, and my boobs tend to be sore more often. However, this past week I have noticed an intense increase in some side effects. My boobs are extremely sore and I am having a mixture of ...Objectives Depo-Provera is an injectable contraceptive method containing medroxyprogesterone acetate. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. Therefore, this study is aimed at to investigate the effects of Depo-Provera on body weight and blood pressure among Ethiopian women. Institution based cross-sectional study ...some people may put on weight when they use Depo-Provera or Sayana Press contraceptive injections; you may experience side effects like headaches, acne, hair loss, decreased sex drive and mood swings; any side effects can continue for as long as the injection lasts (8 or 13 weeks) and for some time after; Risks Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%).Common side effects of Depo-Medrol may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach discomfort, bloating; headache; or. changes in your menstrual periods. This is not a complete list of side effects and others may occur.After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. Mar 3, 2023 · Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women. Medroxyprogesterone acetate. Medroxyprogesterone acetate ( MPA ), also known as depot medroxyprogesterone acetate ( DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [9] [3] It is used as a method of birth control and as a part of menopausal hormone therapy.Long-term effects of injection Depo-Provera (depo-medroxyprogesterone acetate) on carbohydrate and lipid metabolism were studied in 157 women who were treated continuously for a mean duration of 43.3 months. The patients were matched with 162 controls for race, age, parity and height. Glucose tolerance was impaired with higher intolerance at ...Spotting (light bleeding or brown discharge between periods) Not getting your period at all. About half of people stop getting their period while they’re on the shot (don’t worry, this is totally safe). Other possible side effects include: Nausea. Weight gain. Headaches. Sore breasts. Depression.altered interest in having sexual intercourse. abnormal bleeding from the uterus. a problem with menstrual periods. dizziness. weight gain. headache. nervousness. reactions at the site of the ...Depo-Provera use may also delay the return of your fertility. About 50% of women will be able to get pregnant within 10 months after their last Depo-Provera injection, but it can take up to 18 months for fertility to return. Some women report irregular or continuous bleeding when using Depo-Provera along with other unwanted side effects.A person needs a Depo-Provera shot every 3 months to ensure it remains effective in preventing pregnancy. The birth control shot, or depo shot, Depo-Provera, or DMPA, is an injection that a person ...Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone. Aug 15, 2019 · Objectives Depo-Provera is an injectable contraceptive method containing medroxyprogesterone acetate. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. Therefore, this study is aimed at to investigate the effects of Depo-Provera on body weight and blood pressure among Ethiopian women. Institution based cross-sectional study ... Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ... Common side effects of Depo-Medrol may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach discomfort, bloating; headache; or. changes in your menstrual periods. This is not a complete list of side effects and others may occur.

severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest.. What time is mcdonald

depo shot side effects long term

Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ... Methylprednisolone (Medrol) can cause changes in your fluids and electrolytes (e.g., sodium, potassium, and calcium). This can result in high blood pressure, swelling, and kidney problems. In addition, some studies suggest that methylprednisolone (Medrol) can damage the heart if used after a recent heart attack.severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest.Jan 11, 2023 · Appropriate Use. The Depo-Provera birth control shot has advantages and disadvantages compared to other types of birth control. While it's convenient and effective, for example, the Depo shot also carries the risk of side effects like irregular bleeding and bone loss. This article looks at some of the pros and cons of using Depo-Provera. The birth control shot (sometimes called Depo-Provera, the Depo shot, or DMPA) contains the hormone progestin. Progestin stops you from getting pregnant by preventing ovulation. When there’s no egg in the tube, pregnancy can’t happen. It also works by making cervical mucus thicker. When the mucus on the cervix is thicker, the sperm can’t ... Effects on baby A small amount of the synthetic hormones in contraceptives will enter your milk, there is no evidence that this is dangerous to your baby. Some babies younger than six weeks may have difficulty metabolising the hormones and for this reason it is not recommended to start using a hormonal contraceptive until your baby is older. Jan 15, 2022 · itchiness. flushing (warmth and redness or deepening of color in your skin) A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include: swelling under ... Nov 5, 2022 · 9 Common Depo-Provera Side Effects Irregular Menstrual Bleeding. Menstrual cycle changes are the most common side effects of the Depo-Provera shot. Many... No Periods. After a few shots, Depo-Provera may stop menstruation altogether in some people. Others may have very light... Anxiety and Mood ... May 10, 2023 · Rated Depo-Provera for Endometriosis Report . I was always happy and outgoing. Always with friends or making new friends to hang with. After almost 2 years on this drug I am: • Severely depressed • crazy anxiety • antisocial ( I try but I don’t ever want to be with people or do anything the more I get this shot ) • I don’t feel attracted to anyone • I cry everyday at least 5 ... Depo-Provera Contraceptive Injection should not be used as a long-term birth control method (i.e., longer than 2 years) unless other birth control methods are considered inadequate. (See Warnings and Precautions (5.1)). 1 INDICATIONS AND USAGE Depo-Provera CI is indicated only for the prevention of pregnancy. The loss of bone mineral densityThe most common side effects associated with DMPA use are bothersome but benign and typically improve with time or upon discontinuation, including irregular bleeding, weight gain, dizziness, abdominal pain, and anxiety . Occasionally, other side effects do occur and may cause significant distress to the patient.Sep 28, 2021 · One major drawback of Depo-Provera is the continuous or irregular bleeding (spotting) that can sometimes occur during the first year. While this typically occurs during the first few months, it can persist for up to a year or longer for some people. Learn more about this side effect and what you can do if it persists. TEK IMAGE / Getty Images. Long-term effects of injection Depo-Provera (depo-medroxyprogesterone acetate) on carbohydrate and lipid metabolism were studied in 157 women who were treated continuously for a mean duration of 43.3 months. The patients were matched with 162 controls for race, age, parity and height. Glucose tolerance was impaired with higher intolerance at ... .

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